Scientists build a fish out of human heart cells and watch it swim with each beat

“Biohybrid” fish reveal some of the secrets of human hearts. A biohybrid, fish gets hooked. To decode the dynamics of human hearts, researchers at Harvard University and Emory University set up a clever experiment: They created around 500 biohybrid fish, which are artificial other than their tail fins lined with living human heart cells. Then, … Read more

Evolution of the fish heart by sub/neofunctionalization of an elastin gene

Abstract The evolution of phenotypic traits is a key process in diversification of life. However, the mechanisms underlying the emergence of such evolutionary novelties are largely unknown. Here we address the origin of bulbus arteriosus (BA), an organ of evolutionary novelty seen in the teleost heart outflow tract (OFT), which sophisticates their circulatory system. The … Read more

Scientists Build an Artificial Fish That Swims on Its Own Using Human Heart Cells

Scientists Build an Artificial Fish That Swims on Its Own Using Human Heart Cells The experiment could advance pacemaker technology and bring science closer to developing artificial hearts for people Harvard scientists have engineered a school of fish that uses the contractions of human heart cells to swim autonomously. Researchers say the experiment could advance … Read more

Excitation–Contraction Coupling in the Goldfish (Carassius auratus) Intact Heart

ORIGINAL RESEARCH article Sec. Cardiac Electrophysiology Volume 11 – 2020 | https://doi.org/10.3389/fphys.2020.01103 Excitation–Contraction Coupling in the Goldfish (Carassius auratus) Intact Heart 1Quantitative Systems Biology Program, School of Natural Sciences, University of California, Merced, Merced, CA, United States 2Department of Bioengineering, School of Engineering, University of California, Merced, Merced, CA, United States Cardiac physiology of fish … Read more

World’s oldest heart preserved in 380 million-year-old armored fish

A team of Australian scientists has discovered the world’s oldest heart, part of the fossilized remains of an armored fish that died some 380 million years ago. The fish also had a fossilized stomach, liver, and intestine. All the organs were arranged much like similar organs in modern shark anatomy, according to a recent paper … Read more